People

 

Principle Investigator
Andy Hsien-Wei Yeh, Ph.D.
hsyeh@ucsc.edu
Biomolecular Engineering
University of California Santa Cruz
Lab: 205 Baskin Engineering Building
Office: 353C Baskin Engineering Building

Dr. Andy Yeh is an assistant professor of biomolecular engineering at the University of California Santa Cruz. Dr. Yeh thrives in a diverse background and has acquired extensive training and rich research experience in protein engineering, computational protein design, biosensing, enzyme design, directed evolution, synthetic chemistry, and chemical biology. Dr. Yeh enjoys tackling clinically relevant challenges from the perspectives of chemical and biotechnological approaches. The immediate research goal in his research program will focus on (i) building up a set of advanced luminescent probes; (ii) applying protein-based biosensors to clinical diagnostics; and (iii) the use of these molecular machines to monitor and program biological functions. His long-term vision is to combine protein design and novel chemical tools to precisely measure and perturb biological events both in vitro and in vivo and answer a wide range of biological questions. With the recent breakthroughs in de novo protein design, we will more rapidly enter a new age of de novo chemical biology — one not only of discovery but also invention. Dr. Yeh hopes that his research interests will spark a wide range of interdisciplinary collaborations in synthetic biology, drug discovery, and personalized medicine.

 

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